Heart health · For patients and their doctors
Lipoprotein(a), or Lp(a), is a cholesterol particle you inherit from your parents. A high level raises the risk of heart attack and stroke, and a routine lipid profile does not show it. Enter your result to see what it means for you, what your LDL cholesterol should be, and what your family should do.
A guide for you and your doctor, not a prescription. For adults. The risk estimate uses the American PREVENT equations, which were not built on Indian data and may underestimate risk in South Asians. Nothing you enter leaves this device.
The two units measure different things and cannot be converted exactly, so choose the one printed on your report.
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| Lp(a) | Band | Relative ASCVD risk |
|---|---|---|
| Below 30 mg/dL (75 nmol/L) | Rule out (EAS) | 1.0 to 1.2 times |
| 30 to 50 mg/dL (75 to 125 nmol/L) | Grey zone (EAS) | 1.2 to 1.4 times |
| Above 50 mg/dL (125 nmol/L) | Rule in (EAS); risk-enhancing (ACC/AHA 2026) | About 1.4 times at 50 |
| 100 mg/dL (250 nmol/L) | Very high | About 2 times |
| 150 mg/dL | Very high | About 2.7 times |
| Above 180 mg/dL (430 nmol/L) | Extreme: lifetime risk like heterozygous FH (ESC/EAS 2019) | 2.7 times or more |
Relative risks are against a median of 7 mg/dL (EAS 2022, UK Biobank), and were similar in white, black and South Asian people. This check places nmol/L results on the mg/dL table with a factor of 2.5, and applies the relative risk to the PREVENT estimate as a hazard ratio. This is an approximation: PREVENT already reflects the average Lp(a) of its population, so adjusted values may run slightly high, and the 30-year figure is an extrapolation.
| LAI risk group | LDL-C goal | Non-HDL-C goal |
|---|---|---|
| Extreme, group B (CAD with a repeat event on treatment, homozygous FH, or diabetes plus organ damage, polyvascular disease or 2 or more risk factors) | 30 mg/dL or lower | 60 mg/dL or lower |
| Extreme, group A (CAD with diabetes, polyvascular disease, heterozygous FH or 3 or more risk factors) | Below 50 mg/dL; 30 or lower optional | Below 80 mg/dL |
| Very high (other ASCVD; diabetes with organ damage or 2 or more risk factors) | Below 50 mg/dL | Below 80 mg/dL |
| High (3 risk factors; diabetes with 0 or 1 risk factor; FH or LDL-C 190 or more; eGFR below 45; calcium score 100 or more; Lp(a) 50 mg/dL or more) | Below 70 mg/dL | Below 100 mg/dL |
| Moderate (2 risk factors) or low | Below 100 mg/dL | Below 130 mg/dL |
LAI 2023 also describes extreme risk category C (repeat events despite LDL-C around 30 mg/dL; goal about 10 to 15 mg/dL). Groups are summarised from the Lipid Association of India consensus statements; check against the full 2023 update before relying on them. Major risk factors: age (men 45 and over, women 55 and over), family history of premature ASCVD, tobacco, hypertension, low HDL-C.
ACC/AHA 2026, as applied here: ASCVD at very high risk (repeat events, more than one arterial bed, or 2 or more high-risk conditions such as age 65 or more, diabetes, hypertension, CKD, FH or tobacco) LDL-C below 55 mg/dL; other ASCVD below 70 mg/dL; no ASCVD with PREVENT 10-year risk 10% or more below 70 mg/dL; PREVENT 3 to 10% below 100 mg/dL.
Found an error? Write to info@caspianhealthcare.in.