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Blood · For patients and doctors

Anaemia under evaluation

Enter the numbers from your blood report. You get how low your haemoglobin is, what type of anaemia the report shows, the likely causes, the next tests to ask for and when to go to hospital. Doctors get the full work-up: iron indices with the right cut-off, the reticulocyte index, the investigation pathway and treatment notes.

A guide, not a diagnosis. Anaemia is a sign, not a disease: something is causing it, and that cause must be found. Take the result to your doctor. Nothing you enter leaves this page.

Go to hospital now if you have chest pain, breathlessness at rest, fainting, black stools, vomiting of blood or heavy bleeding.

1. About you

Sex
Health and medicines tick all that apply
Symptoms tick all that apply

2. Blood count (CBC)

3. Iron, vitamins and other tests (add what you have)

Peripheral smear says tick what the report mentions
Enter your age and haemoglobin to begin. Every other number makes the answer sharper.

Understanding the report

What haemoglobin and anaemia mean

Haemoglobin is the protein in red blood cells that carries oxygen. Anaemia means the haemoglobin is below the normal level for your age, sex and pregnancy stage. The WHO cut-off for most adult women is 12 g/dL and for adult men 13 g/dL. In India, 57% of women aged 15 to 49 and 25% of men are anaemic (NFHS-5, 2019 to 2021), so it is common. Common does not mean harmless: the cause still needs to be found.

What MCV tells you

MCV is the average size of your red cells. Small cells (low MCV, usually below 80) most often mean iron deficiency or thalassaemia trait. Large cells (high MCV, usually above 100) point to low vitamin B12 or folate, alcohol, thyroid or liver problems, or some medicines. Normal-sized cells point to kidney disease, long-term illness, recent bleeding, or a mix of two deficiencies that cancel each other out.

Why ferritin matters, and why it can mislead

Ferritin shows how much iron the body has stored. A low ferritin means low iron, almost always. But ferritin rises with infection, inflammation, kidney disease and liver disease, so a "normal" ferritin does not rule out low iron in those situations. That is why the doctor may also look at transferrin saturation and CRP.

Thalassaemia trait: why it matters before marriage and pregnancy

About 3 to 4 in 100 Indians carry beta thalassaemia trait. Carriers have small red cells and mild anaemia, but normal iron. Iron tablets do not help them and may harm if given for years. The test is an HPLC (haemoglobin electrophoresis). If both partners are carriers, each pregnancy has a 1 in 4 chance of a child with thalassaemia major, so the partner should be tested too.

Do not start iron or B12 before the tests

Iron tablets, B12 injections and multivitamins change the very results the doctor needs. A ferritin drawn after a week of iron, or a B12 drawn after an injection, can look normal and hide the cause. Get the blood drawn first, then start treatment, unless your doctor says otherwise.

Sources

  1. WHO. Guideline on haemoglobin cutoffs to define anaemia in individuals and populations. 2024. NCBI Bookshelf
  2. WHO. Guideline on use of ferritin concentrations to assess iron status. 2020. NCBI Bookshelf
  3. Snook J, et al. British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults. Gut 2021;70:2030.
  4. Ko CW, et al. AGA clinical practice guidelines on the gastrointestinal evaluation of iron deficiency anemia. Gastroenterology 2020;159:1085.
  5. Devalia V, et al. Guidelines for the diagnosis and treatment of cobalamin and folate disorders. Br J Haematol 2014;166:496.
  6. KDIGO Clinical Practice Guideline for Anemia in CKD, 2012, and the 2026 update. kdigo.org
  7. McDonagh TA, et al. 2021 ESC Guidelines for heart failure. Eur Heart J 2021;42:3599.
  8. Carson JL, et al. Red blood cell transfusion: 2023 AABB international guidelines. JAMA 2023;330:1892.
  9. American Diabetes Association. Standards of Care in Diabetes 2026, Section 3, Recommendation 3.10.
  10. NGSP. Factors that interfere with HbA1c test results. ngsp.org
  11. NICE NG12. Suspected cancer: recognition and referral (colorectal, 2023 update). nice.org.uk
  12. Ministry of Health and Family Welfare. National Family Health Survey 5 (2019 to 2021); Anemia Mukt Bharat. PIB

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