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Patient instruction sheet · Diabetes and hormones

Taking your thyroid tablet

Levothyroxine (thyroxine)

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For anyone taking levothyroxine for an underactive thyroid.

Drawing: The thyroid gland, the tablet bottle, a glass of plain water, a clock, and, kept apart, the cup of tea.
The thyroid gland, the tablet bottle, a glass of plain water, a clock, and, kept apart, the cup of tea.

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How to take it

  1. Take it on an empty stomach, with plain water.
  2. Then wait at least 30 minutes, ideally 60, before tea, coffee, milk or breakfast.
  3. Take it at the same time and in the same way every day. First thing in the morning suits most people.
  4. If mornings are difficult, bedtime is an alternative: at least 3 hours after your last meal. Choose one and keep to it.

Keep a gap from these

WhatGap from the thyroid tablet
Calcium and iron tablets4 hours
Antacids, and vitamins that contain calcium or iron4 hours
Tea, coffee, milk, soya, high-fibre food30 to 60 minutes

Important

Blood tests

Planning a pregnancy, or pregnant?

Tell your doctor at once. The dose usually needs to be raised early in pregnancy, and the test is repeated about every 4 weeks. Ask your doctor now what to do on the day your pregnancy test is positive. Many advise this until you are seen: take your usual tablet every day, and one extra tablet on 2 days of the week (9 tablets a week instead of 7).

Signs the dose may be wrong

Too much

  • Fast heartbeat or palpitations
  • Feeling hot, sweating
  • Nervousness, shaking hands
  • Poor sleep
  • Loss of weight, loose motions

Too little

  • Tiredness
  • Feeling cold
  • Weight gain
  • Constipation
  • Dry skin, puffy face

Do not change the dose yourself. Get a TSH test and see the doctor. Chest pain, or a very fast or irregular heartbeat: go to a hospital.

Questions about this sheet? Call Caspian Healthcare reception on +91 89193 41154. A doctor is on duty at all hours for problems that are not critical. Caspian has no emergency department: in an emergency call 108.

Where this comes from

Prepared by Caspian Healthcare from the sources above. Last reviewed October 2026. General information: your own doctor's written instructions come first.