For people with known angina who have been prescribed a nitrate tablet (isosorbide dinitrate 5 mg or glyceryl trinitrate 0.5 mg) or spray to use when chest pain comes.

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When the chest pain comes
- Stop what you are doing and sit down.
- Put one tablet under your tongue and let it dissolve. Do not chew or swallow it. With a spray: one or two sprays under the tongue, then close your mouth.
- Wait 5 minutes.
- If the pain has not gone, or is getting worse: call 108 now. Do not wait longer.
- While waiting for help, you may take a second dose, and a third after another 5 minutes. Not more than 3 doses in 15 minutes.
If you have aspirin within reach and are not allergic to it, chew 300 to 350 mg while you wait: one soluble aspirin tablet of 325 or 350 mg, or two tablets of 150 mg. Do not go looking for it, and do not delay the call. If you take a blood thinner, take the extra aspirin only if the ambulance team or a doctor tells you to.
It may be a heart attack if there is
- Pressure, squeezing or pain in the chest lasting more than a few minutes
- Pain spreading to the arm, neck, jaw, back or stomach
- Breathlessness, a cold sweat, nausea or light-headedness
- In women, older people and people with diabetes, sometimes only breathlessness, vomiting, unusual tiredness or back pain
Call 108 or go to the nearest hospital with a cardiac emergency service. Caspian has no cath lab, intensive care unit or emergency department. Do not drive yourself.
Never use it if
- You have taken sildenafil or vardenafil in the last 24 hours, or tadalafil in the last 48 hours. Together they cause a dangerous fall in blood pressure. Do not take the nitrate. Call 108 and tell the emergency doctor exactly what you took.
What to expect
- Headache, flushing and dizziness are common and pass. This is why you must sit down first.
- If you feel faint, lie down and raise your legs.
- Paracetamol can be taken for the headache.
Using it wisely
- Carry it with you always. Keep some by the bed.
- You can take one dose 5 to 10 minutes before an activity that usually brings on the pain.
- Glyceryl trinitrate tablets in a bottle lose strength quickly: keep them in the original glass bottle, tightly closed, and throw away what is left 8 weeks after opening. Tablets in a strip stay in the strip until needed. Check the expiry date.
- Keep it away from heat and sunlight. Not in a shirt pocket against the body all day.
See your doctor the same day if
- The pain is coming more often, with less effort, or at rest
- You are needing the tablet more than before
- The pain wakes you at night
A change in the pattern is a warning, even if each attack settles.
Questions about this sheet? Call Caspian Healthcare reception on +91 89193 41154. A doctor is on duty at all hours for problems that are not critical. Caspian has no emergency department: in an emergency call 108.
Where this comes from
- Nitroglycerin sublingual tablets: US prescribing information, DailyMed
- MedlinePlus (US National Library of Medicine): angina, when you have chest pain
- NHS: how and when to take glyceryl trinitrate
- Tadalafil: US prescribing information (interval before nitrates), DailyMed
- British Heart Foundation: aspirin in a suspected heart attack
- American Heart Association: warning signs of a heart attack
Prepared by Caspian Healthcare from the sources above. Last reviewed October 2026. General information: your own doctor's written instructions come first.