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Patient instruction sheet · Diabetes and hormones

Sick day rules for diabetes

Fever, vomiting, loose motions or any illness

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For anyone with diabetes who is unwell with fever, vomiting, loose motions or an infection.

Drawing: A thermometer, drinking water, a glucometer, your tablets, and a bowl of soup.
A thermometer, drinking water, a glucometer, your tablets, and a bowl of soup.

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The five rules

  1. Never stop your insulin, even if you are not eating. Illness usually pushes sugar up, and you may need more insulin. Long-acting insulin is needed every day. If you are not eating and your sugar is falling, mealtime or premixed insulin may need reducing: call your doctor.
  2. Test more often. On insulin: every 2 to 4 hours, including at night. On tablets: at least 4 times a day.
  3. Drink. A glass (about 200 ml) every hour while awake, unless your doctor has limited your fluids. Small sips every 15 minutes if you feel sick.
  4. Keep some food going in. If you cannot eat meals, take a small amount every 1 to 2 hours. Any one of: half a glass of fruit juice, a glass of milk, a cup of soup, or two plain biscuits.
  5. Pause the medicines in the table while you are vomiting, have loose motions or cannot drink.

Medicines to pause while you are losing fluid

MedicineWhy
Any medicine ending in -gliflozin (dapagliflozin, empagliflozin, remogliflozin and others, alone or in a combination tablet)Can cause a dangerous acid build-up (ketoacidosis) during illness, even when the sugar reading is normal.
MetforminCan build up if the kidneys are affected by dehydration.
Blood pressure tablets ending in -pril or -sartan, and tablets that make you pass more urine (such as furosemide or torsemide)Can harm the kidneys when you are short of fluid.
Painkillers such as ibuprofen and diclofenacThe same reason. Use paracetamol instead.
Glimepiride, gliclazide and similar tabletsCan cause low sugar if you are not eating. Ask the doctor whether to reduce or skip.

Start them again 24 to 48 hours after you are eating and drinking normally. If you take a weekly injection for diabetes or weight and are vomiting, ask the doctor before the next dose.

Check ketones

If you have type 1 diabetes, are pregnant, or take a -gliflozin medicine, test for ketones whenever your sugar is above 250 mg/dL, you are vomiting, or you feel very unwell. Use a blood ketone meter or urine ketone strips.

Blood ketones (mmol/L)Urine stripWhat to do
Below 0.6NegativeNormal. Keep testing.
0.6 to 1.5Trace or +Drink more. Test again in 2 hours.
1.6 to 2.9++Call your doctor now. You may need extra insulin.
3.0 or more+++ or moreEmergency. Go to hospital.

Go to a hospital now if

Call 108 or go to the nearest hospital with an emergency department.

Questions about this sheet? Call Caspian Healthcare reception on +91 89193 41154. A doctor is on duty at all hours for problems that are not critical. Caspian has no emergency department: in an emergency call 108.

Where this comes from

Prepared by Caspian Healthcare from the sources above. Last reviewed October 2026. General information: your own doctor's written instructions come first.